B1 - High-resolution analysis of the dynamic interaction network that enables optoribogenetics in vitro and in cellulo

Project-related Publications

[P1] G. Pietruschka, A.T. Ranzani, A. Weber, T. Patwari, S. Pilsl, C. Renzl, D.M. Otte, D. Pyka, A. Möglich, G. Mayer*
“An RNA Motif That Enables Optozyme Control and Light-Dependent Gene Expression in Bacteria and Mammalian Cells“
Adv. Sci. 2024, 2304519. DOI: 10.1002/advs.202304519.

[P2] J. Borggräfe, C.G.W. Gertzen, A. Viegas, H. Gohlke*, M. Etzkorn*
“The architecture of the 10-23 DNAzyme and its implications for DNA-mediated catalysis”
FEBS J. 2023, 290, 2011–2021. DOI: 10.1111/febs.16698.

[P3] J. Borggräfe, J. Victor, H. Rosenbach, A. Viegas, C.G.W. Gertzen, C. Wuebben, H. Kovacs, M. Gopalswamy, D. Riesner, G. Steger, O. Schiemann, H. Gohlke, I. Span, M. Etzkorn*
“Time-resolved structural analysis of an RNA-cleaving DNA catalyst”
Nature 2022, 601, 144–149. DOI: 10.1038/s41586-021-04225-4.

[P4] A. Dubey, N. Stoyanov, T. Viennet, S. Chhabra, S. Elter, J. Borggräfe, A. Viegas, R.P. Nowak, N. Burdzhiev, O. Petrov, E.S. Fischer, M. Etzkorn*, V. Gelev*, H. Arthanari*
“Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems”
Angew. Chem. Int. Ed. 2021, 60, 13783–13787. DOI: 10.1002/anie.202016070.

[P5] C. Renzl, A. Kakoti, G. Mayer*
“Aptamer-Mediated Reversible Transactivation of Gene Expression by Light”
Angew. Chem. Int. Ed. 2020, 59, 22414–22418. DOI: 10.1002/anie.202009240.

[P6] S. Pilsl, C. Morgan, M. Choukeife, A. Möglich A, G. Mayer*
“Optoribogenetic control of regulatory RNA molecules”
Nat. Commun. 2020, 11, 4825. DOI: 10.1038/s41467-020-18673-5.

[P7] H. Rosenbach, J. Victor, J. Borggräfe, R. Biehl, G. Steger, M. Etzkorn, I. Span*
“Expanding crystallization tools for nucleic acid complexes using U1A protein variants”
J. Struct. Biol. 2020, 210, 107480. DOI: 10.1016/j.jsb.2020.107480.

[P8] A. Viegas, D.M. Yin, J. Borggräfe, T. Viennet, M. Falke, A. Schmitz*, M. Famulok, M. Etzkorn*
“Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment”
Structure 2020, 28, 54–62. DOI: 10.1016/j.str.2019.11.001.

[P9] A.M. Weber, J. Kaiser, T. Ziegler, S. Pilsl, C. Renzl, L. Sixt, G. Pietruschka, S. Moniot, A Kakoti, M. Juraschitz, S. Schrottke, L. Lledo Bryant, C. Steegborn, R. Bittl, G. Mayer*, A Möglich*
“A blue light receptor that mediates RNA binding and translational regulation”
Nat. Chem. Biol. 2019, 15, 1085–1092. DOI: 10.1038/s41589-019-0346-y.

[P10] L.A. Torres-Fernández, B. Jux, M. Bille, Y. Port, K. Schneider, M. Geyer, G. Mayer, W. Kolanus*
“The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21”
Nucleic Acids Res. 2019, 47, 11861–11879. DOI: 10.1093/nar/gkz1057.