Universität Bonn

B4 - A DNA rotaxane molecular automaton regulated by transcribed mRNA: molecular mechanisms and transcriptional control in vitro and in cellulo

Project Area B
Abstract
CV Famulok

Project-related Publications

[P1] Z. Yu, M. Centola, J. Valero*, M. Matthies, P. Šulc, M. Famulok*
“A Self-Regulating DNA Rotaxane Linear Actuator Driven by Chemical Energy”
J. Am. Chem. Soc. 2021, 143, 13292–13298. DOI: 10.1021/jacs.1c06226.

[P2] A. Viegas, D.M. Yin, J. Borggräfe, T. Viennet, M. Falke, A. Schmitz, M. Famulok*, M. Etzkorn*
“Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment”
Structure 2020, 28, 54–62. DOI: 10.1016/j.str.2019.11.001.

[P3] J. Valero, N. Pal, S. Dhakal, N.G. Walter, M. Famulok*
“A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks”
Nat. Nanotechnol. 2018, 13, 496–503. DOI: 10.1038/s41565-018-0109-z.

[P4] D.M. Yin, J.S. Hannam, A. Schmitz, O. Schiemann, G. Hagelueken*, M. Famulok*
“Studying the Conformation of a Receptor Tyrosine Kinase in Solution by Inhibitor-Based Spin Labeling”
Angew. Chem. Int. Ed. 2017, 56, 8417–8421. DOI: 10.1002/anie.201703154.

[P5] M. Centola, J. Valero, M. Famulok*
“Allosteric Control of Oxidative Catalysis by a DNA Rotaxane Nanostructure”
J. Am. Chem. Soc. 2017, 139,16044–16047. DOI: 10.1021/jacs.7b08839.

[P6] M. Kerzhner, D. Abdullin, J. Więcek, H. Matsuoka, G. Hagelueken, O. Schiemann*, M. Famulok*
“Post-synthetic Spin-Labeling of RNA through Click Chemistry for PELDOR Measurements”
Chemistry 2016, 22, 12113–12121. DOI: 10.1002/chem.201601897.

[P7] F. Lohmann, J. Weigandt, J. Valero, M. Famulok*
“Logic gating by macrocycle displacement using a double-stranded DNA [3]rotaxane shuttle”
Angew. Chem. Int. Ed. 2014, 53, 10372–10376. DOI: 10.1002/anie.201405447.

[P8] T. Li, M. Famulok*
“I-motif-programmed functionalization of DNA nanocircles”
J. Am. Chem. Soc. 2013, 135, 1593–1599. DOI: 10.1021/ja3118224.

[P9] F. Lohmann, D. Ackermann, M. Famulok*
“Reversible light switch for macrocycle mobility in a DNA rotaxane”
J. Am. Chem. Soc. 2012, 134, 11884–11887. DOI: 10.1021/ja3042096.

[P10] D. Ackermann, T.L. Schmidt, J.S. Hannam, C.S. Purohit, A. Heckel, M. Famulok*
“A double-stranded DNA rotaxane”
Nat. Nanotechnol. 2010, 5, 436–442. DOI: 10.1038/nnano.2010.65.