C1 - Trityl Spin Labels: Developing Labeling Strategies for in cellulo and Temperature Dependent Pulsed Dipolar EPR Measurements on Nucleic Acid Complexes

Project-related Publications

[P1] L. Bornewasser, C. Domnick, S. Kath-Schorr*
“Stronger together for in-cell translation: natural and unnatural base modified mRNA”
Chem. Sci. 2022, 13, 4753–4761. DOI: 10.1039/D2SC00670G.

[P2] N. Fleck, C. Heubach, T. Hett, S. Spicher, S. Grimme, O. Schiemann*
“Ox‐SLIM: Synthesis of and Site‐Specific Labelling with a Highly Hydrophilic Trityl Spin Label”
Chem. Eur. J. 2021, 27, 5292–5297. DOI: 10.1002/chem.202100013.

[P3] N. Fleck, C.A. Heubach, T. Hett, F.R. Haege, P.P. Bawol, H. Baltruschat, O. Schiemann*
“SLIM: A short-linked, highly redox-stable trityl label for high sensitivity in-cell EPR distance measurements”
Angew. Chem. Int. Ed. 2020, 59, 9767–9772. DOI: 10.1002/anie.202004452.

[P4] C. Wuebben, M.F. Vicino, M. Mueller, O. Schiemann*
“Do the P1 and P2 hairpins of the Guanidine-II Riboswitch interact?”
Nucleic Acids Res. 2020, 48, 10518–10526. DOI: 10.1093/nar/gkaa703.

[P5] C. Domnick, F. Eggert, C. Wuebben, L. Bornewasser, G. Hagelueken, O. Schiemann*, S. Kath-Schorr*
“EPR distance measurements on long non‐coding RNAs empowered by genetic alphabet expansion transcription”
Angew. Chem. Int. Ed. 2020, 59, 7891–7896. DOI: 10.1002/anie.201916447.

[P6] C. Domnick, G. Hagelueken, F. Eggert, O. Schiemann, S. Kath-Schorr*
“Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition”
Org. Biomol. Chem. 2019, 17, 1805–1808. DOI: 10.1039/C8OB02597E.

[P7] C. Wuebben, S. Blume, D. Abdullin, D. Brajtenbach, F. Haege, S. Kath-Schorr, O. Schiemann*
“Site-Directed Spin Labeling of RNA with a gem-Diethylisoindoline Spin Label: PELDOR, Relaxation and Reduction Stability”
Molecules 2019, 24, 4482. DOI: 10.3390/molecules24244482.

[P8] M. Kerzhner, H. Matsuoka, C. Wuebben, M. Famulok*, O. Schiemann*
“High-yield spin labeling of long RNAs for Electron Paramagnetic Resonance Spectroscopy”
Biochemistry 2018, 57, 2923–2931. DOI: 10.1021/acs.biochem.8b00040.

[P9] F. Eggert, S. Kath-Schorr*
“A cyclopropene-modified nucleotide for site-specific RNA labeling using genetic alphabet expansion transcription”
Chem. Commun. 2016, 52, 7284–7287. DOI: 10.1039/C6CC02321E.

[P10] T.J. Wilson, Y. Liu, C. Domnick, S. Kath-Schorr, D.M.J. Lilley*
“The novel chemical mechanism of the twister ribozyme”
J. Am. Chem. Soc. 2016, 138, 6151–6162. DOI: 10.1021/jacs.5b11791.