Z2 - Synthetic and enzymatic preparation of chemically modified nucleic acids

Project-related Publications

[P1] H. Depmeier, S. Kath-Schorr*
“Expanding the Horizon of the Xeno Nucleic Acid Space: Threose Nucleic Acids with Increased Information Storage”
J. Am. Chem. Soc. 2024, ASAP, DOI: 10.1021/jacs.3c14626.

[P2] L. Bornewasser, C. Domnick, S. Kath-Schorr*
“Stronger together for in-cell translation: natural and unnatural base modified mRNA”
Chem. Sci. 2022, 13, 4753–4761. DOI: 10.1039/D2SC00670G.

[P3] L. Bornewasser, S. Kath-Schorr*
“Preparation of site-specifically spin-labeled RNA by in vitro transcription using an expanded genetic alphabet”
Meth. Mol. Biol. 2022, 2439, 223–240. DOI: 10.1007/978-1-0716-2047-2_15.

[P4] M.F. Vicino, C. Wuebben, M. Kerzhner, M. Famulok, O. Schiemann*
”Spin Labeling of Long RNAs Via Click Reaction and Enzymatic Ligation”
Methods Mol. Biol. 2022, 2439, 205–221. DOI: 10.1007/978-1-0716-2047-2_14.

[P5] C. Wuebben, M.F. Vicino, M. Mueller, O. Schiemann*
“Do the P1 and P2 hairpins of the Guanidine-II Riboswitch interact?”
Nucleic Acids Res. 2020, 48, 10518–10526. DOI: 10.1093/nar/gkaa703.

[P6] C. Domnick, F. Eggert, C. Wuebben, L. Bornewasser, G. Hagelueken, O. Schiemann*, S. Kath-Schorr*
“EPR distance measurements on long non‐coding RNAs empowered by genetic alphabet expansion transcription”
Angew. Chem. Int. Ed. 2020, 59, 7891–7896. DOI: 10.1002/anie.201916447.

[P7] C. Domnick, G. Hagelueken, F. Eggert, O. Schiemann, S. Kath-Schorr*
“Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition”
Org. Biomol. Chem. 2019, 17,1805–1808. DOI: 10.1039/C8OB02597E.

[P8] C. Wuebben, S. Blume, D. Abdullin, D. Brajtenbach, F. Haege, S. Kath-Schorr, O. Schiemann*
“Site-Directed Spin Labeling of RNA with a gem-Diethylisoindoline Spin Label: PELDOR, Relaxation and Reduction Stability”
Molecules 2019, 24, 4482. DOI: 10.3390/molecules24244482.

[P9] F. Eggert, K. Kulikov, C. Domnick, P. Leifels, S. Kath-Schorr*
“Illuminated by foreign letters - Strategies for site-specific cyclopropene modification of large functional RNAs via in vitro transcription”
Methods 2017, 120, 17–27. DOI: 10.1016/j.ymeth.2017.04.021.

[P10] F. Eggert, S. Kath-Schorr*
“A cyclopropene-modified nucleotide for site-specific RNA labeling using genetic alphabet expansion transcription”
Chem. Commun. 2016, 52, 7284–7287. DOI: 10.1039/C6CC02321E.